2023 Conference Agenda

Mark Johnston, MD, FRCPC, Director CNS Research/Medical Director, Atlantic, Centricity Research

While clinical evidence is beginning to show the potential and promise for psychedelics as a public health good, the industry lives somewhat in the shadows of Bad Pharma and a tarred history dating back to the 1960s. Drawing on existing research, theoretical standpoints on corporate social responsibility and parts of a secondary analysis of biotech microdosing companies’ websites this talk explores what responsible business may look like for the psychedelic industry. The talk will also include the challenges lying ahead as conversations around legislative changes progress. Key themes that will be covered include the compounds quality, accessibility to the treatment, the management of commercial interests, the sustainability and environmental impact of infrastructure, and inclusivity and diversity across those working in the industry.
Charlotte Smith, Ph.D., Associate Professor in Management and Organisation, University of Leicester

Randomized, placebo controlled clinical trials are intended to isolate drug specific therapeutic effects. This classical style of study has always been limited when applied to psychoactive drugs and psychotherapy, but never more so than with psychedelic therapeutics. In this session, the panelists will make the case that, rather than abandon structured trials altogether, a suite of highly creative and innovative methods can help medical scientists adapt to the challenge of understanding psychedelics.
Joshua Woolley, MD, Ph.D., Associate Professor, Psychiatry, UCSF Weill Institute for Neurosciences
Boris Heifets, MD, Ph.D., Assistant Professor of Anesthesiology, Perioperative & Pain Medicine, Stanford University

Visit the scientific poster session, network with colleagues over coffee and snacks, visit with our exhibitors and meet new people via our meeting scheduling solution.

During specific periods of brain development, the nervous system exhibits heightened sensitivity to ethologically relevant stimuli, as well as increased malleability for synaptic, circuit, and behavioral modifications. These mechanistically constrained windows of time are called critical periods and neuroscientists have long sought methods to reopen them for therapeutic benefit. Dr. Dolen will present evidence that the ability to reopen critical periods is a common neurobiological mechanism that can account for shared therapeutic effects of psychedelics. These results have significant implications for the implementation of psychedelics in clinical practice, as well as the design of novel compounds for the treatment of neuropsychiatric disease.
Gul Dolen, MD, Ph.D., Associate Professor of Neuroscience, Brain Institute, Wendy Klag Center, Johns Hopkins University

We have numerous options for your lunch experience. Join colleagues in our dedicated lunch space, eat in the restaurant, eat outside on the restaurant patio, or take a box lunch and retire to your guest room for some quiet time.

• The main barriers to clinical trials and how to overcome them. (Eg. challenges of getting Schedule 1 licenses, lack of expertise in psychedelic trial design, managing groupthink, participant recruitment, inclusion/exclusion criteria, finding and training therapists, ensuring consistency of therapy, and getting the 'setting' right.)
• The utility (or lack thereof) of pre-clinical testing with psychedelic compounds
• How the FDA, MHRA & EMA differ in approach to these treatments
• What's next for trials in this space

MDMA has an apparently novel therapeutic mechanism that is distinct from classical psychedelics and that may offer benefits in a wide range of CNS disorders. This presentation will describe the history of attempts to develop novel compounds that improve on MDMA, summarizing both the scientific and IP landscapes.
Mathew Baggott, Ph.D., Co-Founder & CEO, Tactogen

Visit the scientific poster session, network with colleagues over coffee and snacks, visit with our exhibitors and meet new people via our meeting scheduling solution.

This presentation invites the consideration of a trauma-informed approach to psychedelic research by means of study design, facilitation approach, and the attention to diversity and inclusion principles. By applying trauma-informed psychotherapeutic practices to facilitation processes such as assessment, preparation and integration of psychedelic experiences, research studies can mitigate the impact of trauma activation and dysregulation in participants suffering from PTSD or complex trauma. Study design can also mitigate the potential for traumatizing experiences through consideration of dose amount and number of sessions in each protocol. Attention to diversity and inclusion principles are important related concerns in psychedelic research to not reproduce previously established anti-ethical research practices in the medical field, holding an inclusive therapeutic frame for participants of various cultural backgrounds to safely participate in psychedelic research.
Gisele Fernandes-Osterhold, MFT, Director of Psychedelic Facilitation, Translational Psychedelic Research Program (TrPR), BAND Lab, University of California San Francisco